Jump to main content
Jump to site search

Issue 21, 2018
Previous Article Next Article

Regioselective nitration of anilines with Fe(NO3)3·9H2O as a promoter and a nitro source

Author affiliations

Abstract

An efficient Fe(NO3)3·9H2O promoted ortho-nitration reaction of aniline derivatives has been developed. This reaction may go through a nitrogen dioxide radical (NO2˙) intermediate, which is generated by the thermal decomposition of iron(III) nitrate. The practicality of the present method using nontoxic and inexpensive iron reagents has been shown by the broad substrate scope and applications.

Graphical abstract: Regioselective nitration of anilines with Fe(NO3)3·9H2O as a promoter and a nitro source

Back to tab navigation

Supplementary files

Article information


Submitted
10 Apr 2018
Accepted
03 May 2018
First published
03 May 2018

Org. Biomol. Chem., 2018,16, 3881-3884
Article type
Communication

Regioselective nitration of anilines with Fe(NO3)3·9H2O as a promoter and a nitro source

Y. Gao, Y. Mao, B. Zhang, Y. Zhan and Y. Huo, Org. Biomol. Chem., 2018, 16, 3881
DOI: 10.1039/C8OB00841H

Social activity

Search articles by author

Spotlight

Advertisements