Issue 19, 2018

Metal-free oxidative decarbonylative alkylation of chromones using aliphatic aldehydes

Abstract

A decarbonylative alkylation of chromones via radical conjugate addition under metal-free conditions was developed using aliphatic aldehydes as alkylating reagents. A series of 2-tertiary, secondary, and even primary alkylated chromanones were obtained in moderate to excellent yields.

Graphical abstract: Metal-free oxidative decarbonylative alkylation of chromones using aliphatic aldehydes

Supplementary files

Article information

Article type
Communication
Submitted
26 Mar 2018
Accepted
15 Apr 2018
First published
17 Apr 2018

Org. Biomol. Chem., 2018,16, 3568-3571

Metal-free oxidative decarbonylative alkylation of chromones using aliphatic aldehydes

R. Chen, J. Yu and J. Cheng, Org. Biomol. Chem., 2018, 16, 3568 DOI: 10.1039/C8OB00720A

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