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Issue 9, 2018
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Alkylating probes for the G-quadruplex structure and evaluation of the properties of the alkylated G-quadruplex DNA

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Abstract

The G-quadruplex structure has been found in biologically significant regions of the genomic DNA, including the telomere and promoter regions, and is known to play an important role in a number of biological processes. In this paper, we report the development of alkylating probes for the G-quadruplex structure and evaluation of the properties of the modified G-quadruplex structure.

Graphical abstract: Alkylating probes for the G-quadruplex structure and evaluation of the properties of the alkylated G-quadruplex DNA

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Article information


Submitted
25 Dec 2017
Accepted
30 Jan 2018
First published
30 Jan 2018

Org. Biomol. Chem., 2018,16, 1436-1441
Article type
Communication

Alkylating probes for the G-quadruplex structure and evaluation of the properties of the alkylated G-quadruplex DNA

N. Sato, S. Takahashi, H. Tateishi-Karimata, M. E. Hazemi, T. Chikuni, K. Onizuka, N. Sugimoto and F. Nagatsugi, Org. Biomol. Chem., 2018, 16, 1436
DOI: 10.1039/C7OB03179C

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