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Issue 2, 2018
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Total synthesis of selaginpulvilins A and C

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An efficient formal total synthesis of two compounds from the selaginpulvilin family of natural products, selaginpulvilin A and C, has been successfully achieved. The tetradehydro Diels–Alder (TDDA) reaction between an enyne and alkyne has been utilized for the creation of the necessary fluorene skeleton. Attempts at the conversion of selaginpulvilin A to selaginpulvilin B, F and H were unsuccessful.

Graphical abstract: Total synthesis of selaginpulvilins A and C

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The article was received on 24 Oct 2017, accepted on 01 Dec 2017 and first published on 01 Dec 2017

Article type: Paper
DOI: 10.1039/C7OB02609A
Org. Biomol. Chem., 2018,16, 262-265

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    Total synthesis of selaginpulvilins A and C

    B. S. Chinta and B. Baire, Org. Biomol. Chem., 2018, 16, 262
    DOI: 10.1039/C7OB02609A

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