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Issue 33, 2017
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A general and convenient palladium-catalyzed synthesis of benzylideneindolin-3-ones with formic acid as the CO source

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Abstract

A general and convenient palladium-catalyzed carbonylative synthesis of 2-benzylideneindolin-3-ones from 2-iodoanilines and arylacetylenes has been developed. With formic acid as the CO source and Ac2O as the activator, a variety of 2-benzylideneindolin-3-ones were obtained in good to excellent yields with exceptional functional group tolerance.

Graphical abstract: A general and convenient palladium-catalyzed synthesis of benzylideneindolin-3-ones with formic acid as the CO source

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Article information


Submitted
27 Jun 2017
Accepted
01 Aug 2017
First published
01 Aug 2017

Org. Biomol. Chem., 2017,15, 6905-6908
Article type
Communication

A general and convenient palladium-catalyzed synthesis of benzylideneindolin-3-ones with formic acid as the CO source

R. Li, X. Qi and X. Wu, Org. Biomol. Chem., 2017, 15, 6905
DOI: 10.1039/C7OB01557G

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