Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.

Issue 17, 2017
Previous Article Next Article

Copper(i)-catalyzed ring-opening cyanation of cyclopropanols

Author affiliations


A copper(I)-catalyzed ring-opening cyanation of cyclopropanols was developed. The reaction provides an alternative method to achieve β-cyano ketones efficiently. This reaction exhibits good functional group compatibility under mild conditions and can be scaled up to the gram scale. Preliminary mechanistic studies suggest that the reaction might go through a free radical process.

Graphical abstract: Copper(i)-catalyzed ring-opening cyanation of cyclopropanols

Back to tab navigation

Supplementary files

Article information

14 Mar 2017
06 Apr 2017
First published
06 Apr 2017

Org. Biomol. Chem., 2017,15, 3590-3593
Article type

Copper(I)-catalyzed ring-opening cyanation of cyclopropanols

Y. Feng, Y. Shu, P. Cao, T. Xu and H. Xu, Org. Biomol. Chem., 2017, 15, 3590
DOI: 10.1039/C7OB00627F

Social activity

Search articles by author