Jump to main content
Jump to site search

Issue 12, 2017
Previous Article Next Article

Copper-catalyzed TEMPO oxidative cleavage of 1,3-diketones and β-keto esters for the synthesis of 1,2-diketones and α-keto esters

Author affiliations

Abstract

A copper-catalyzed efficient and practical method has been developed for the synthesis of 1,2-diketones and α-keto esters. TEMPO was used as a radical initiator and scavenger, oxidizing the cleavage of α-methylene of 1,3-diketones and β-keto esters to form 1,2-diketones and α-keto esters. This method provided a general way for the formation of 1,2-dicarbonyl compounds.

Graphical abstract: Copper-catalyzed TEMPO oxidative cleavage of 1,3-diketones and β-keto esters for the synthesis of 1,2-diketones and α-keto esters

Back to tab navigation

Supplementary files

Article information


Submitted
31 Jan 2017
Accepted
28 Feb 2017
First published
28 Feb 2017

Org. Biomol. Chem., 2017,15, 2629-2637
Article type
Paper

Copper-catalyzed TEMPO oxidative cleavage of 1,3-diketones and β-keto esters for the synthesis of 1,2-diketones and α-keto esters

P. Zhou, C. Li, S. Zhou, A. Shoberu and J. Zou, Org. Biomol. Chem., 2017, 15, 2629
DOI: 10.1039/C7OB00241F

Social activity

Search articles by author

Spotlight

Advertisements