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Issue 7, 2017
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Synthesis of aminopyrazoles from sydnones and ynamides

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Abstract

Aminopyrazoles are prepared from readily accessible sydnones and sulfonyl ynamides using either a copper-mediated sydnone alkyne cycloaddition (CuSAC) or in situ generated strained cyclic ynamides.

Graphical abstract: Synthesis of aminopyrazoles from sydnones and ynamides

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Article information


Submitted
17 Nov 2016
Accepted
16 Jan 2017
First published
25 Jan 2017

Org. Biomol. Chem., 2017,15, 1575-1579
Article type
Communication

Synthesis of aminopyrazoles from sydnones and ynamides

T. Wezeman, J. Comas-Barceló, M. Nieger, J. P. A. Harrity and S. Bräse, Org. Biomol. Chem., 2017, 15, 1575
DOI: 10.1039/C6OB02518H

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