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Issue 4, 2017
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Carboxylatopillar[n]arenes: a versatile class of water soluble synthetic receptors

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Abstract

Carboxylatopillar[n]arenes (CP[n]As, n = 5, 6, 7, 9, 10) are water soluble derivatives of pillar[n]arenes. The three-dimensional π-electron-rich cavity and carboxylate groups at the portals, enabled CP[n]A to have strong binding affinity in water, which has been successfully harnessed in fabricating responsive supramolecular assemblies from supra-amphiphiles and developing targeted drug delivery systems (DDSs). CP[n]A based supraamphiphiles have also been used for sensor applications. This review highlights the diverse applications of water soluble carboxylatopillar[n]arenes.

Graphical abstract: Carboxylatopillar[n]arenes: a versatile class of water soluble synthetic receptors

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Article information


Submitted
11 Oct 2016
Accepted
02 Dec 2016
First published
02 Dec 2016

Org. Biomol. Chem., 2017,15, 762-772
Article type
Review Article

Carboxylatopillar[n]arenes: a versatile class of water soluble synthetic receptors

S. Dasgupta and P. S. Mukherjee, Org. Biomol. Chem., 2017, 15, 762
DOI: 10.1039/C6OB02214F

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