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Issue 4, 2017
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Enantioselective synthesis of spirooxindole benzoquinolizines via organo-catalyzed cascade reactions

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Abstract

A Michael–Mannich–hemiaminalization–dehydration cascade reaction was developed for the construction of spirooxindole benzoquinolizine derivatives. Additionally, spirooxindole benzoindolizidine was prepared conveniently through a ring-contracted rearrangement reaction from spirooxindole benzoquinolizine.

Graphical abstract: Enantioselective synthesis of spirooxindole benzoquinolizines via organo-catalyzed cascade reactions

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Submitted
04 Oct 2016
Accepted
27 Oct 2016
First published
27 Oct 2016

Org. Biomol. Chem., 2017,15, 778-781
Article type
Communication

Enantioselective synthesis of spirooxindole benzoquinolizines via organo-catalyzed cascade reactions

Y. Tan, E. Feng, Q. Sun, H. Lin, X. Sun, G. Lin and X. Sun, Org. Biomol. Chem., 2017, 15, 778
DOI: 10.1039/C6OB02157C

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