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Issue 38, 2016
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Cascade bicyclization of triethylammonium thiolates with hydrazines: efficient access to pyrazolo[3,4-c]quinolines

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Abstract

A new bicyclization strategy has been established, allowing a flexible and practical approach to 33 examples of pyrazolo[3,4-c]quinolines from low-cost and readily accessible triethylammonium thiolates with hydrazines. Notably, the features of this work include broad functional group compatibility, mild reaction conditions and good reaction yields.

Graphical abstract: Cascade bicyclization of triethylammonium thiolates with hydrazines: efficient access to pyrazolo[3,4-c]quinolines

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Article information


Submitted
10 Aug 2016
Accepted
31 Aug 2016
First published
01 Sep 2016

Org. Biomol. Chem., 2016,14, 9080-9087
Article type
Paper

Cascade bicyclization of triethylammonium thiolates with hydrazines: efficient access to pyrazolo[3,4-c]quinolines

W. Fan, Y. Li, B. Jiang and G. Li, Org. Biomol. Chem., 2016, 14, 9080
DOI: 10.1039/C6OB01728B

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