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Issue 28, 2016
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An aerobic Cu-mediated practical approach to aromatic nitriles using cyanide anions as the nitrogen source

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Abstract

A Cu-mediated cyanation of aryl methyl ketones using cyanide anions as the nitrogen source was achieved to provide aromatic nitriles in moderate to good yields. The reaction tolerates a variety of synthetically important functional groups.

Graphical abstract: An aerobic Cu-mediated practical approach to aromatic nitriles using cyanide anions as the nitrogen source

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Publication details

The article was received on 12 Jun 2016, accepted on 14 Jun 2016 and first published on 23 Jun 2016


Article type: Communication
DOI: 10.1039/C6OB01269H
Org. Biomol. Chem., 2016,14, 6687-6690

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    An aerobic Cu-mediated practical approach to aromatic nitriles using cyanide anions as the nitrogen source

    L. Gu, C. Jin, H. Zhang, J. Liu, Ganpeng Li and Z. Yang, Org. Biomol. Chem., 2016, 14, 6687
    DOI: 10.1039/C6OB01269H

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