Issue 31, 2016
From the journal:

Organic & Biomolecular Chemistry

A rare γ-pyranopyrazole skeleton: design, one-pot synthesis and computational study†

Muhammed Üçüncü,a   Ceren Cantürk,a   Erman Karakuş,a   Hüseyin Zeybek,a   Uğur Bozkaya,b   Emine Soydaş,c   Ertan Şahinc  and  Mustafa Emrullahoğlu*a  

* Corresponding authors

a Department of Chemistry, Faculty of Science, İzmir Institute of Technology, Izmir, Urla, Turkey
E-mail: mustafaemrullahoglu@iyte.edu.tr

b Department of Chemistry, Hacettepe University, Ankara 06800, Turkey

c Department of Chemistry, Atatürk University, Erzurum 25240, Turkey

Abstract

Drawing upon a consecutive amide coupling and intramolecular cyclisation pathway, a one-pot, straightforward synthetic route has been developed for a range of pyrazole fused γ-pyrone derivatives. The reaction mechanism proposed for the chemoselective formation of γ-pyranopyrazole is furthermore fully supported by experimental and computational studies.

Graphical abstract: A rare γ-pyranopyrazole skeleton: design, one-pot synthesis and computational study

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C6OB01099G
Article type
Paper
Submitted
19 May 2016
Accepted
05 Jul 2016
First published
05 Jul 2016
This article is Open Access
Creative Commons BY-NC license

Org. Biomol. Chem., 2016,14, 7490-7494

Permissions

Request permissions

A rare γ-pyranopyrazole skeleton: design, one-pot synthesis and computational study

M. Üçüncü, C. Cantürk, E. Karakuş, H. Zeybek, U. Bozkaya, E. Soydaş, E. Şahin and M. Emrullahoğlu, Org. Biomol. Chem., 2016, 14, 7490 DOI: 10.1039/C6OB01099G

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. You can use material from this article in other publications, without requesting further permission from the RSC, provided that the correct acknowledgement is given and it is not used for commercial purposes.

To request permission to reproduce material from this article in a commercial publication, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party commercial publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements