Issue 26, 2016

Scalable procedure for the fragmentation of hydroperoxides mediated by copper and iron tetrafluoroborate salts

Abstract

An improved protocol for the formal elimination of propene from organic substrates is reported. This process entails the ozonolytic conversion of an alkene to a methoxy hydroperoxide which undergoes fragmentation mediated by copper and iron. The use of soluble Cu(BF4)2 and Fe(BF4)2 results in reproducible results up to a 100 gram scale.

Graphical abstract: Scalable procedure for the fragmentation of hydroperoxides mediated by copper and iron tetrafluoroborate salts

Supplementary files

Article information

Article type
Communication
Submitted
30 Apr 2016
Accepted
25 May 2016
First published
07 Jun 2016

Org. Biomol. Chem., 2016,14, 6197-6200

Scalable procedure for the fragmentation of hydroperoxides mediated by copper and iron tetrafluoroborate salts

D. Huang, A. W. Schuppe, M. Z. Liang and T. R. Newhouse, Org. Biomol. Chem., 2016, 14, 6197 DOI: 10.1039/C6OB00941G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements