Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.


Issue 24, 2016
Previous Article Next Article

Synthesis of 4H-chromenes by an unexpected, K3PO4-mediated intramolecular Rauhut–Currier type reaction

Author affiliations

Abstract

In an attempt to develop the umpolung of Michael acceptors using chalcones having an enoate moiety under N-heterocyclic carbene (NHC) catalysis, a K3PO4-mediated intramolecular Rauhut–Currier type reaction was observed. This C(sp2)–C(sp2) coupling reaction afforded the biologically important 4H-chromenes in moderate to good yields. It is likely that the enol ether functionality acts as the nucleophilic trigger in this reaction.

Graphical abstract: Synthesis of 4H-chromenes by an unexpected, K3PO4-mediated intramolecular Rauhut–Currier type reaction

  • This article is part of the themed collection: New Talent
Back to tab navigation

Supplementary files

Article information


Submitted
26 Mar 2016
Accepted
19 Apr 2016
First published
19 Apr 2016

Org. Biomol. Chem., 2016,14, 5612-5616
Article type
Communication

Synthesis of 4H-chromenes by an unexpected, K3PO4-mediated intramolecular Rauhut–Currier type reaction

A. Bhunia, S. R. Yetra, R. G. Gonnade and A. T. Biju, Org. Biomol. Chem., 2016, 14, 5612
DOI: 10.1039/C6OB00654J

Social activity

Search articles by author

Spotlight

Advertisements