Various difunctionalizations of acrylamide: an efficient approach to synthesize oxindoles

Abstract

Various difunctionalizations of acrylamide can not only provide a simple approach to form a wide scope of functionalized oxindoles, but can also be applied and generated easily. This review concludes different difunctionalizations of acrylamide to synthesize oxindoles based on the mechanistic aspects. The goal is to encourage further mechanistic studies hopefully leading to an in-depth understanding of this strategy.