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Issue 24, 2016

Trihaloethenes as versatile building blocks for organic synthesis

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Abstract

This review highlights the chemistry of trihaloethene building blocks with a special focus on commercially available 1,1,2-trichloroethene. The topics surveyed herein include the use of trihaloethenes as C2-building blocks for transition metal-catalyzed coupling reactions, addition, elimination and cycloaddition reactions as well as natural product syntheses.

Graphical abstract: Trihaloethenes as versatile building blocks for organic synthesis

  • This article is part of the themed collection: New Talent

Article information


Submitted
13 Jan 2016
Accepted
26 Jan 2016
First published
26 Jan 2016

This article is Open Access

Org. Biomol. Chem., 2016,14, 5377-5389
Article type
Review Article

Trihaloethenes as versatile building blocks for organic synthesis

A. S. Grossmann and T. Magauer, Org. Biomol. Chem., 2016, 14, 5377 DOI: 10.1039/C6OB00091F

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