Jump to main content
Jump to site search

Issue 30, 2015
Previous Article Next Article

One-pot synthesis of spiropyrroloquinoline-isoindolinone and their aza-analogs via the Ugi-4CR/metal-free intramolecular bis-annulation process

Author affiliations

Abstract

This presentation discloses a one-pot synthesis of a series of spiropyrroloquinoline isoindolinone and spiropyrroloquinoline aza-isoindolinone scaffolds. The reaction proceeds by the combination of a Ugi four-component reaction (4CR) and two intramolecular cyclizations under metal-free conditions. The proof of the structures relies on analytical investigation and X-ray crystallography.

Graphical abstract: One-pot synthesis of spiropyrroloquinoline-isoindolinone and their aza-analogs via the Ugi-4CR/metal-free intramolecular bis-annulation process

Back to tab navigation

Supplementary files

Publication details

The article was received on 01 Jun 2015, accepted on 25 Jun 2015 and first published on 25 Jun 2015


Article type: Paper
DOI: 10.1039/C5OB01095K
Author version
available:
Download author version (PDF)
Org. Biomol. Chem., 2015,13, 8211-8220

  •   Request permissions

    One-pot synthesis of spiropyrroloquinoline-isoindolinone and their aza-analogs via the Ugi-4CR/metal-free intramolecular bis-annulation process

    M. Ghandi, N. Zarezadeh and A. Abbasi, Org. Biomol. Chem., 2015, 13, 8211
    DOI: 10.1039/C5OB01095K

Search articles by author

Spotlight

Advertisements