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Issue 15, 2015
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Copper-mediated tandem reaction of β-ketoesters/ketones with tertiary amines for the synthesis of 2,3-dihydrofurans

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Abstract

A copper-mediated tandem reaction of β-ketoesters/ketones with tertiary amines was achieved, which provides a simple and efficient approach to the synthesis of 2,3-dihydrofuran derivatives. In this tandem reaction, the tertiary amine not only offers the methylene moiety but also serves as the base.

Graphical abstract: Copper-mediated tandem reaction of β-ketoesters/ketones with tertiary amines for the synthesis of 2,3-dihydrofurans

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Article information


Submitted
30 Jan 2015
Accepted
10 Mar 2015
First published
10 Mar 2015

Org. Biomol. Chem., 2015,13, 4426-4429
Article type
Communication

Copper-mediated tandem reaction of β-ketoesters/ketones with tertiary amines for the synthesis of 2,3-dihydrofurans

S. Guo, L. Lu, J. Gong, Z. Zhu, F. Xu, Z. Wei and H. Cai, Org. Biomol. Chem., 2015, 13, 4426
DOI: 10.1039/C5OB00191A

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