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Issue 7, 2015
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β-Ketothioamides: efficient reagents in the synthesis of heterocycles

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Abstract

β-Ketothioamides (KTAs) are versatile building blocks for the rapid construction of various heterocyclic compounds. In the past decade, a number of successful reactions based on KTAs have been developed for the construction of heterocyclic skeletons under mild conditions. This minireview focuses on the annulation reactions of KTAs with dielectrophilic or dinucleophilic reagents. Multicomponent reactions using KTAs to construct various heterocycles are also the major contents in this review.

Graphical abstract: β-Ketothioamides: efficient reagents in the synthesis of heterocycles

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Article information


Submitted
23 Sep 2014
Accepted
10 Dec 2014
First published
10 Dec 2014

Org. Biomol. Chem., 2015,13, 1942-1953
Article type
Review Article
Author version available

β-Ketothioamides: efficient reagents in the synthesis of heterocycles

W. Guo, L. Wen and M. Li, Org. Biomol. Chem., 2015, 13, 1942
DOI: 10.1039/C4OB02024C

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