Jump to main content
Jump to site search

Issue 37, 2014
Previous Article Next Article

Facile synthesis of 5-hydroxy-l-lysine from d-galactose as a chiral-precursor

Author affiliations

Abstract

A concise synthesis of (2S,5R) and (2S,5S)-5-hydroxy-lysine was achieved by utilizing D-galactose as a chiral-precursor with stereo retention. This synthetic strategy showcased the potential of utilizing carbohydrates as starting materials to prepare amino acids. Using the diazido intermediate, the derived β-D-galactopyranosyl and α-D-glucopyranosyl-(1→2)-β-D-galactosyl moieties were synthesized.

Graphical abstract: Facile synthesis of 5-hydroxy-l-lysine from d-galactose as a chiral-precursor

Back to tab navigation

Supplementary files

Article information


Submitted
13 Jun 2014
Accepted
23 Jul 2014
First published
29 Jul 2014

Org. Biomol. Chem., 2014,12, 7310-7317
Article type
Paper

Facile synthesis of 5-hydroxy-L-lysine from D-galactose as a chiral-precursor

L. Guo, T. Liu, K. Chen, T. Song, P. G. Wang and W. Zhao, Org. Biomol. Chem., 2014, 12, 7310
DOI: 10.1039/C4OB01220H

Social activity

Search articles by author

Spotlight

Advertisements