Issue 31, 2014

C3-Symmetric chiral trisimidazoline-catalyzed Friedel–Crafts (FC)-type reaction

Abstract

Imidazoline-catalyzed enantioselective Friedel–Crafts (FC)-type reactions were established using C3-symmetric chiral trisimidazolines. The imidazoline catalysts promoted the FC-type reaction of aldimines with 2-naphthols to produce the corresponding adducts in high yields with up to 99% ee.

Graphical abstract: C 3-Symmetric chiral trisimidazoline-catalyzed Friedel–Crafts (FC)-type reaction

Supplementary files

Article information

Article type
Communication
Submitted
06 May 2014
Accepted
19 Jun 2014
First published
20 Jun 2014

Org. Biomol. Chem., 2014,12, 5827-5830

Author version available

C 3-Symmetric chiral trisimidazoline-catalyzed Friedel–Crafts (FC)-type reaction

S. Takizawa, S. Hirata, K. Murai, H. Fujioka and H. Sasai, Org. Biomol. Chem., 2014, 12, 5827 DOI: 10.1039/C4OB00925H

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements