Issue 25, 2014

Asymmetric synthesis of tetrahydroquinolines through supramolecular organocatalysis

Abstract

Functionalized chiral tetrahydroquinolines were synthesized through supramolecular organocatalysis using quinidine-NH-thiourea 3c/L-phenylalanine 4i followed by reductive amination from the simple substrates.

Graphical abstract: Asymmetric synthesis of tetrahydroquinolines through supramolecular organocatalysis

Supplementary files

Article information

Article type
Communication
Submitted
15 Mar 2014
Accepted
28 Apr 2014
First published
29 Apr 2014

Org. Biomol. Chem., 2014,12, 4300-4304

Author version available

Asymmetric synthesis of tetrahydroquinolines through supramolecular organocatalysis

D. B. Ramachary and K. S. Shruthi, Org. Biomol. Chem., 2014, 12, 4300 DOI: 10.1039/C4OB00570H

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