Jump to main content
Jump to site search

Issue 33, 2013
Previous Article Next Article

Combined C–H functionalization/O–H insertion reaction to form tertiary β-alkoxy substituted β-aminophosphonates catalyzed by [Cu(MeCN)4]PF6

Author affiliations

Abstract

The copper-catalyzed C–H functionalization/O–H insertion reaction of α-diazophosphonates with alcohols has been developed with iodine as an additive. In order to understand this reaction, we present here a possible mechanism for the combined reaction. This process provides straightforward access to tertiary β-alkoxy substituted β-aminophosphonate derivatives with moderate to good yields.

Graphical abstract: Combined C–H functionalization/O–H insertion reaction to form tertiary β-alkoxy substituted β-aminophosphonates catalyzed by [Cu(MeCN)4]PF6

Back to tab navigation

Supplementary files

Article information


Submitted
09 May 2013
Accepted
02 Jul 2013
First published
02 Jul 2013

Org. Biomol. Chem., 2013,11, 5491-5499
Article type
Paper

Combined C–H functionalization/O–H insertion reaction to form tertiary β-alkoxy substituted β-aminophosphonates catalyzed by [Cu(MeCN)4]PF6

Y. Cai, Y. Lu, C. Yu, H. Lyu and Z. Miao, Org. Biomol. Chem., 2013, 11, 5491
DOI: 10.1039/C3OB40941D

Social activity

Search articles by author

Spotlight

Advertisements