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Issue 43, 2012

A cucurbit[8]uril sponge

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Abstract

This paper describes a convenient approach to quantitative removal of the synthetic host cucurbit[8]uril (Q8) from aqueous mixtures using a sepharose resin coated in memantine groups to selectively sequester Q8 in the presence of competing hosts and guests. The “Q8 sponge” can separate Q8 from Q6 and reverse the Q8-mediated dimerization of peptides.

Graphical abstract: A cucurbit[8]uril sponge

Supplementary files

Article information


Submitted
09 Sep 2012
Accepted
26 Sep 2012
First published
05 Oct 2012

Org. Biomol. Chem., 2012,10, 8587-8589
Article type
Communication

A cucurbit[8]uril sponge

V. Ramalingam, S. K. Kwee, L. M. Ryno and A. R. Urbach, Org. Biomol. Chem., 2012, 10, 8587 DOI: 10.1039/C2OB26774H

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