Jump to main content
Jump to site search

Issue 39, 2012
Previous Article Next Article

Rationally-designed fluorescent lysine riboswitch probes

Author affiliations

Abstract

Two fluorescent lysine amide analogs, in which the carboxyl end of lysine was covalently attached to dansyl or NBD groups through an ethylene glycol-based linker, were rationally designed and synthesized. Both probes showed high binding affinity to the lysine riboswitch in vitro and their fluorescence intensities decreased by riboswitch binding.

Graphical abstract: Rationally-designed fluorescent lysine riboswitch probes

Back to tab navigation

Supplementary files

Article information


Submitted
18 Jun 2012
Accepted
01 Sep 2012
First published
04 Sep 2012

Org. Biomol. Chem., 2012,10, 7872-7874
Article type
Communication

Rationally-designed fluorescent lysine riboswitch probes

P. Budhathoki, L. F. Bernal-Perez, O. Annunziata and Y. Ryu, Org. Biomol. Chem., 2012, 10, 7872
DOI: 10.1039/C2OB26160J

Social activity

Search articles by author

Spotlight

Advertisements