Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.


Issue 24, 2011
Previous Article Next Article

Divergent synthetic approach to 6′′-modified α-GalCer analogues

Author affiliations

Abstract

A synthetic approach is presented for the synthesis of galacturonic acid and D-fucosyl modified KRN7000. The approach allows for late-stage functionalisation of both the sugar 6′′-OH and the sphingosine amino groups, which enables convenient synthesis of promising 6′′-modified KRN7000 analogues.

Graphical abstract: Divergent synthetic approach to 6′′-modified α-GalCer analogues

Back to tab navigation

Supplementary files

Article information


Submitted
23 Jul 2011
Accepted
02 Sep 2011
First published
02 Sep 2011

Org. Biomol. Chem., 2011,9, 8413-8421
Article type
Paper

Divergent synthetic approach to 6′′-modified α-GalCer analogues

N. Pauwels, S. Aspeslagh, G. Vanhoenacker, K. Sandra, E. D. Yu, D. M. Zajonc, D. Elewaut, B. Linclau and S. Van Calenbergh, Org. Biomol. Chem., 2011, 9, 8413
DOI: 10.1039/C1OB06235B

Social activity

Search articles by author

Spotlight

Advertisements