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Issue 14, 2011
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Fast and efficient microwave-assisted synthesis of functionalized peptoids viaUgi reactions

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Abstract

A wide range of N-alkylglycines (peptoids) can be efficiently prepared viaUgi reactions using microwave irradiations. The results confirm the versatility and efficiency of the methodology for the preparation of functionalized peptoids. The products can be used in consecutive Ugi reactions to yield cyclic peptoids of potential biological interest.

Graphical abstract: Fast and efficient microwave-assisted synthesis of functionalized peptoids viaUgi reactions

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Supplementary files

Article information


Submitted
24 Mar 2011
Accepted
16 May 2011
First published
16 May 2011

Org. Biomol. Chem., 2011,9, 5024-5027
Article type
Communication

Fast and efficient microwave-assisted synthesis of functionalized peptoids viaUgi reactions

A. D. F. S. Barreto, O. E. Vercillo, M. A. Birkett, J. C. Caulfield, L. A. Wessjohann and C. K. Z. Andrade, Org. Biomol. Chem., 2011, 9, 5024 DOI: 10.1039/C1OB05471F

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