Issue 8, 2011
From the journal:

Organic & Biomolecular Chemistry

Phenazinolins A–E: novel diphenazines from a tin mine tailings-derived Streptomyces species†

Zhang-Gui Ding,a   Ming-Gang Li,a   Jie Ren,b   Jiang-Yuan Zhao,a   Rong Huang,a   Qing-Zhong Wang,a   Xiao-Long Cui,a   Hua-Jie Zhu*b  and  Meng-Liang Wen*a  

* Corresponding authors

a Key Laboratory for Microbial Resources, Key Laboratory of Medicinal Chemistry for Natural Resources, Ministry of Education, Yunnan Institute of Microbiology, Yunnan University, PR China
E-mail: mlwen@ynu.edu.cn
Fax: +86 871 503 2170

b State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, PR China
E-mail: hjzhu@mail.kib.ac.cn

Abstract

Phenazinolins A–E (1–5), which possess a carbon skeleton unique to diphenazines (the azabicyclo[3.3.1]nonadienol moiety in 1–3 and the oxabicyclo[3.3.1]nonadienol moiety in 4 and 5), were isolated from tin mine tailings-derived Streptomyces diastaticusYIM DT26, with 1–3 exhibited appreciable cytotoxicity and antibiotic effects.

Graphical abstract: Phenazinolins A–E: novel diphenazines from a tin mine tailings-derived Streptomyces species

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Article information

DOI
https://doi.org/10.1039/C1OB05044C
Article type
Paper
Submitted
08 Jan 2011
Accepted
17 Jan 2011
First published
19 Jan 2011

Org. Biomol. Chem., 2011,9, 2771-2776

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Phenazinolins A–E: novel diphenazines from a tin mine tailings-derived Streptomyces species

Z. Ding, M. Li, J. Ren, J. Zhao, R. Huang, Q. Wang, X. Cui, H. Zhu and M. Wen, Org. Biomol. Chem., 2011, 9, 2771 DOI: 10.1039/C1OB05044C

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