Issue 1, 2011

Mutated variant of Candida antarcticalipase B in (S)-selective dynamic kinetic resolution of secondary alcohols

Abstract

An (S)-selective dynamic kinetic resolution of secondary alcohols, employing a mutated variant of Candida antarcticalipase B (CalB) gave products in 84–88% yield and in 90–97% ee.

Graphical abstract: Mutated variant of Candida antarcticalipase B in (S)-selective dynamic kinetic resolution of secondary alcohols

Supplementary files

Article information

Article type
Communication
Submitted
20 Sep 2010
Accepted
29 Oct 2010
First published
17 Nov 2010

Org. Biomol. Chem., 2011,9, 81-82

Mutated variant of Candida antarcticalipase B in (S)-selective dynamic kinetic resolution of secondary alcohols

K. Engström, M. Vallin, P. Syrén, K. Hult and Jan-E. Bäckvall, Org. Biomol. Chem., 2011, 9, 81 DOI: 10.1039/C0OB00748J

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