Atropisomeric 8-arylchromen-4-ones exhibit enantioselective inhibition of the DNA-dependent protein kinase (DNA-PK)
Abstract
Substitution at the 3-position of the
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* Corresponding authors
a
Northern Institute for Cancer Research, School of Chemistry, Bedson Building, Newcastle University, Newcastle upon Tyne, United Kingdom
E-mail:
celine.cano@ncl.ac.uk
Tel: 44 (0)1912227060
b KuDOS Pharmaceuticals, Ltd., 410 Cambridge Science Park, Milton Road, Cambridge, United Kingdom
Substitution at the 3-position of the
C. Cano, B. T. Golding, K. Haggerty, I. R. Hardcastle, M. Peacock and R. J. Griffin, Org. Biomol. Chem., 2010, 8, 1922 DOI: 10.1039/B926245H
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