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Issue 19, 2009
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A colorimetric and fluorescent merocyanine-based probe for biological thiols

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Abstract

A new “dual-mode” chromogenic and fluorescent turn-on probe (2) for the selective sensing of biological thiols is reported. In MeOH–H2O cosolvent at physiological pH 7.40 (MeOH–H2O = 3:7), biological thiols cleave the 2,4-dinitrobenzenesulfonyl group to release the chromo- and fluorophore merocyanine (3).

Graphical abstract: A colorimetric and fluorescent merocyanine-based probe for biological thiols

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Supplementary files

Article information


Submitted
19 May 2009
Accepted
09 Jul 2009
First published
10 Aug 2009

Org. Biomol. Chem., 2009,7, 4017-4020
Article type
Paper

A colorimetric and fluorescent merocyanine-based probe for biological thiols

S. Wang, W. Deng, D. Sun, M. Yan, H. Zheng and J. Xu, Org. Biomol. Chem., 2009, 7, 4017
DOI: 10.1039/B909760K

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