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Issue 17, 2009
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Palladium-catalysed synthesis of 1-isoindolecarboxylic acid esters and sequential Diels–Alder reactions: access to bridged- and fused-ring heterocycles

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Abstract

The Pd-catalysed intramolecular α-arylation of α-amino acid esters provides a useful methodology for the synthesis of substituted isoindole derivatives, which have been used in Diels–Alder reactions to access diverse skeletal frameworks.

Graphical abstract: Palladium-catalysed synthesis of 1-isoindolecarboxylic acid esters and sequential Diels–Alder reactions: access to bridged- and fused-ring heterocycles

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Publication details

The article was received on 18 May 2009, accepted on 02 Jul 2009 and first published on 09 Jul 2009


Article type: Communication
DOI: 10.1039/B909701E
Citation: Org. Biomol. Chem., 2009,7, 3382-3384

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    Palladium-catalysed synthesis of 1-isoindolecarboxylic acid esters and sequential Diels–Alder reactions: access to bridged- and fused-ring heterocycles

    D. Solé and O. Serrano, Org. Biomol. Chem., 2009, 7, 3382
    DOI: 10.1039/B909701E

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