A new one-pot hydroformylation/Strecker synthesis as a versatile synthetic tool for polyfunctional compounds and functionalization of dendrimers

Abstract

A versatile and high yielding one-pot hydroformylation/Strecker synthesis is reported for the synthesis of various α-aminonitriles. This methodology allows functionalization of dendrimers (e.g.polyamines 4–7) and hyper branched polymers (e.g. polyallyl glycerol 12) to give corresponding dendritic structures with α-aminonitriles and/or amino acids in the outer shell in good to excellent yields.