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Issue 19, 2009
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A new one-pot hydroformylation/Strecker synthesis as a versatile synthetic tool for polyfunctional compounds and functionalization of dendrimers

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Abstract

A versatile and high yielding one-pot hydroformylation/Strecker synthesis is reported for the synthesis of various α-aminonitriles. This methodology allows functionalization of dendrimers (e.g.polyamines 4–7) and hyper branched polymers (e.g. polyallyl glycerol 12) to give corresponding dendritic structures with α-aminonitriles and/or amino acids in the outer shell in good to excellent yields.

Graphical abstract: A new one-pot hydroformylation/Strecker synthesis as a versatile synthetic tool for polyfunctional compounds and functionalization of dendrimers

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Article information


Submitted
23 Apr 2009
Accepted
24 Jun 2009
First published
24 Jul 2009

Org. Biomol. Chem., 2009,7, 4000-4008
Article type
Paper

A new one-pot hydroformylation/Strecker synthesis as a versatile synthetic tool for polyfunctional compounds and functionalization of dendrimers

M. A. Subhani, K. Müller, F. Koç and P. Eilbracht, Org. Biomol. Chem., 2009, 7, 4000
DOI: 10.1039/B907787A

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