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Issue 11, 2009
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New development of glycan arrays

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Abstract

The development of glycan arrays has enabled the high-sensitivity and high-throughput analysis of carbohydrate–protein interactions and contributed to significant advances in glycomics. A number of new array platforms that allow for qualitative and quantitative analysis of mono- and multivalent interactions on surfaces have been developed recently. Glycan arrays are not only a powerful tool for basic research, but also a promising technique for medical diagnosis, and detection of pathogens and cancers. These studies also have led to the design of efficient carbohydrate-based antimicrobial or anticancer vaccines.

Graphical abstract: New development of glycan arrays

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Publication details

The article was received on 05 Feb 2009 and first published on 27 Apr 2009


Article type: Perspective
DOI: 10.1039/B902510N
Org. Biomol. Chem., 2009,7, 2247-2254

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    New development of glycan arrays

    C. Wu, P. Liang and C. Wong, Org. Biomol. Chem., 2009, 7, 2247
    DOI: 10.1039/B902510N

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