Issue 14, 2008
From the journal:

Organic & Biomolecular Chemistry

Concise synthesis of the tricyclic core of lycoposerramine S†‡

Mark C. Elliott,*a   Nahed N. E. El Sayeda  and  James S. Painea  

* Corresponding authors

a School of Chemistry, Cardiff University, Main College Building, Park Place, Cardiff, UK
E-mail: elliottmc@cardiff.ac.uk
Fax: +44 (0)29 20874030
Tel: +44 (0)29 20874686

Abstract

The tricyclic core of lycoposerramine S has been synthesised in 10 steps from a symmetrical cyclohexadiene precursor by way of a desymmetrising free-radical cyclisation and iodocyclisation.

Graphical abstract: Concise synthesis of the tricyclic core of lycoposerramine S

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Article information

DOI
https://doi.org/10.1039/B804664F
Article type
Paper
Submitted
18 Mar 2008
Accepted
14 Apr 2008
First published
16 May 2008

Org. Biomol. Chem., 2008,6, 2611-2618

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Concise synthesis of the tricyclic core of lycoposerramine S

M. C. Elliott, N. N. E. El Sayed and J. S. Paine, Org. Biomol. Chem., 2008, 6, 2611 DOI: 10.1039/B804664F

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