Jump to main content
Jump to site search

Issue 4, 2008
Previous Article Next Article

On the reactivity of 6-acetyl-7-(2-dimethylaminovinyl)pyrazolo[1,5-a]pyrimidines with 1,3- and 1,4-bisnucleophiles

Author affiliations

Abstract

Reaction of 6-acetyl-7-(2-dimethylaminovinyl)pyrazolo[1,5-a]pyrimidine 1 with 1,3- and 1,4-bisnucleophiles has been investigated; obtainment of new polycyclic heterocyclic derivatives is reported. A convenient procedure leading to new pyrazolo[1,5-a]quinazolines is described; a modest bioactivity of these compounds against two human tumor cell lines was also ascertained.

Graphical abstract: On the reactivity of 6-acetyl-7-(2-dimethylaminovinyl)pyrazolo[1,5-a]pyrimidines with 1,3- and 1,4-bisnucleophiles

Back to tab navigation

Article information


Submitted
19 Nov 2007
Accepted
13 Dec 2007
First published
14 Jan 2008

Org. Biomol. Chem., 2008,6, 739-744
Article type
Paper

On the reactivity of 6-acetyl-7-(2-dimethylaminovinyl)pyrazolo[1,5-a]pyrimidines with 1,3- and 1,4-bisnucleophiles

S. Chimichi, M. Boccalini, S. Selleri, C. Costagli, G. Guerrini and G. Viola, Org. Biomol. Chem., 2008, 6, 739
DOI: 10.1039/B717835B

Social activity

Search articles by author

Spotlight

Advertisements