Initiation of lipid autoxidation by ABAP at pH 4–10 in SDS micelles

Abstract

The rates of radical generation, R_i, by two water soluble initiators: 2,2′-azobis(2-methylpropionamidine) and 2,2′-azobis[2-methyl-N-(2-hydroxyethyl)propionamide], and the lipid soluble 2,2′-azobisisobutyronitrile were measured in an SDS micellar system over a pH range of 4–10. Enhanced values of R_i at low pH are attributed to Coulombic repulsion of protonated radicals.