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Issue 15, 2007
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Total synthesis of luotonin A and 14-substituted analogues

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Abstract

A new and concise synthesis of luotonin A was achieved from the previously described compounds ethyl 4-oxo-3,4-dihydroquinazoline-2-carboxylate and 1-(2-nitrophenyl)prop-2-en-1-one. New 14-substituted luotonin A analogues were prepared using 14-chloroluotonin A as the key intermediate.

Graphical abstract: Total synthesis of luotonin A and 14-substituted analogues

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Publication details

The article was received on 22 May 2007, accepted on 12 Jun 2007 and first published on 29 Jun 2007


Article type: Paper
DOI: 10.1039/B707684C
Org. Biomol. Chem., 2007,5, 2486-2490

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    Total synthesis of luotonin A and 14-substituted analogues

    J. J. Mason and J. Bergman, Org. Biomol. Chem., 2007, 5, 2486
    DOI: 10.1039/B707684C

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