Issue 1, 2007
From the journal:

Organic & Biomolecular Chemistry

Enantioselective synthesis of C3 fluoro-MEP

Stephanos Ghilagaber,a   William N. Huntera  and  Rodolfo Marquez†*b  

* Corresponding authors

a School of Life Sciences, University of Dundee, UK

b WestCHEM, Department of Chemistry, University of Glasgow, Glasgow, UK
E-mail: r.marquez@chem.gla.ac.uk
Fax: +44 (0)141 330 4888
Tel: +44 (0)141 330 8491

Abstract

The first enantioselective synthesis of C3 fluoro-MEP is herein reported. The synthetic pathway developed takes advantage of a selective hydrofluorination of a 2,3-epoxy-1-alcohol to introduce the required tertiary fluoride unit.

Graphical abstract: Enantioselective synthesis of C3 fluoro-MEP

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Article information

DOI
https://doi.org/10.1039/B613656G
Article type
Paper
Submitted
19 Sep 2006
Accepted
20 Oct 2006
First published
10 Nov 2006

Org. Biomol. Chem., 2007,5, 97-102

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Enantioselective synthesis of C3 fluoro-MEP

S. Ghilagaber, W. N. Hunter and R. Marquez, Org. Biomol. Chem., 2007, 5, 97 DOI: 10.1039/B613656G

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