Issue 22, 2006

Synthesis, oligonucleotide incorporation and base pair stability of 7-methyl-8-oxo-2′-deoxyguanosine

Abstract

7-Methyl-8-oxo-2′-deoxyguanosine, an analogue of the abundant promutagen 8-oxo-2′-deoxyguanosine, was incorporated into oligonucleotides and tested for its stability in various base pairs.

Graphical abstract: Synthesis, oligonucleotide incorporation and base pair stability of 7-methyl-8-oxo-2′-deoxyguanosine

Supplementary files

Article information

Article type
Communication
Submitted
04 Sep 2006
Accepted
03 Oct 2006
First published
13 Oct 2006

Org. Biomol. Chem., 2006,4, 4068-4070

Synthesis, oligonucleotide incorporation and base pair stability of 7-methyl-8-oxo-2′-deoxyguanosine

M. L. Hamm and K. Billig, Org. Biomol. Chem., 2006, 4, 4068 DOI: 10.1039/B612597B

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