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Issue 23, 2006
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Efficient Friedel–Crafts alkylation of indoles and pyrrole with enones and nitroalkene in water

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Abstract

An operationally simple and entirely green protocol for heteropoly acid (10 mg) catalyst conjugate addition of indoles and pyrrole to unsaturated carbonyl compounds and nitroalkene in water at ambient temperature in good to excellent yields has been developed.

Graphical abstract: Efficient Friedel–Crafts alkylation of indoles and pyrrole with enones and nitroalkene in water

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Publication details

The article was received on 18 Jul 2006, accepted on 06 Oct 2006 and first published on 17 Oct 2006


Article type: Communication
DOI: 10.1039/B610263H
Org. Biomol. Chem., 2006,4, 4275-4277

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    Efficient Friedel–Crafts alkylation of indoles and pyrrole with enones and nitroalkene in water

    N. Azizi, F. Arynasab and M. R. Saidi, Org. Biomol. Chem., 2006, 4, 4275
    DOI: 10.1039/B610263H

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