Issue 14, 2006

Tandem azidination– and hydroazidination–Huisgen [3 + 2] cycloadditions of ynamides. Synthesis of chiral amide-substituted triazoles

Abstract

Tandem azidination– and hydroazidination–Huisgen [3 + 2] cycloadditions of ynamides are described here. These processes are regioselective and chemoselective, leading to the synthesis of chiral amide-substituted triazoles.

Graphical abstract: Tandem azidination– and hydroazidination–Huisgen [3 + 2] cycloadditions of ynamides. Synthesis of chiral amide-substituted triazoles

Supplementary files

Article information

Article type
Communication
Submitted
11 May 2006
Accepted
05 Jun 2006
First published
16 Jun 2006

Org. Biomol. Chem., 2006,4, 2679-2682

Tandem azidination– and hydroazidination–Huisgen [3 + 2] cycloadditions of ynamides. Synthesis of chiral amide-substituted triazoles

X. Zhang, R. P. Hsung and L. You, Org. Biomol. Chem., 2006, 4, 2679 DOI: 10.1039/B606680A

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