A new approach to combretastatin D2

David Cousin; John Mann; Mark Nieuwenhuyzen; Hendrik van den Berg

doi:10.1039/B513515J

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A new approach to combretastatin D₂†

David Cousin,^a John Mann,*^a Mark Nieuwenhuyzen^a and Hendrik van den Berg^b

Author affiliations

* Corresponding authors

^a School of Chemistry, Queen′s University Belfast, Stranmillis Rd., Belfast, UK

^b Department of Oncology, Queen's University Belfast, Belfast City Hospital, Lisburn Rd., Belfast, UK

Abstract

A concise and convergent route to combretastatin D₂ is described together with some preliminary biological data.

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Supplementary files

Crystal structure data TXT (14K)

Article information

DOI: https://doi.org/10.1039/B513515J
Article type: Paper
Submitted: 23 Sep 2005
Accepted: 25 Oct 2005
First published: 25 Nov 2005

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Org. Biomol. Chem., 2006,4, 54-62

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A new approach to combretastatin D₂

D. Cousin, J. Mann, M. Nieuwenhuyzen and H. van den Berg, Org. Biomol. Chem., 2006, 4, 54 DOI: 10.1039/B513515J

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Organic & Biomolecular Chemistry