Issue 22, 2005
From the journal:

Organic & Biomolecular Chemistry

Mechanistic divergence of two closely related aldol-like enzyme-catalysed reactions†

Meekyung Ahn,a   Amy L. Pietersma,a   Linley R. Schofielda  and  Emily J. Parker*a  

* Corresponding authors

a Institute of Fundamental Sciences, Massey University, Private Bag 11-222, Palmerston North, New Zealand
E-mail: E.J.Parker@massey.ac.nz
Fax: +64 6 350 5682
Tel: +64 6 356 9099

Abstract

The analysis of the interaction of threose 4-phosphate and 2-deoxyerythrose 4-phosphate with 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (DAH7PS) reveals previously unrecognised mechanistic differences between the DAH7PS-catalysed reaction and that catalysed by the closely related enzyme, 3-deoxy-D-manno-octulosonate 8-phosphate synthase (KDO8PS).

Graphical abstract: Mechanistic divergence of two closely related aldol-like enzyme-catalysed reactions

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/B511661A
Article type
Communication
Submitted
16 Aug 2005
Accepted
23 Sep 2005
First published
06 Oct 2005

Org. Biomol. Chem., 2005,3, 4046-4049

Permissions

Request permissions

Mechanistic divergence of two closely related aldol-like enzyme-catalysed reactions

M. Ahn, A. L. Pietersma, L. R. Schofield and E. J. Parker, Org. Biomol. Chem., 2005, 3, 4046 DOI: 10.1039/B511661A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements