Issue 3, 2005
From the journal:

Organic & Biomolecular Chemistry

Carbolithiation of gem-aryl disubstituted methylenecyclopropanes†

Jin-Wen Huanga  and  Min Shi*ab  

* Corresponding authors

a State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Road, Shanghai, China

b East China University of Science and Technology, 130 Mei Long Lu, Shanghai, China
E-mail: mshi@pub.sioc.ac.cn
Fax: 86-21-64166128

Abstract

A novel carbolithiation of gem-aryl disubstituted methylenecyclopropanes was disclosed by the treatment with BuLi in THF at −78 °C. The corresponding addition products can be obtained in good to high yields by quenching with various electrophiles.

Graphical abstract: Carbolithiation of gem-aryl disubstituted methylenecyclopropanes

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Article information

DOI
https://doi.org/10.1039/B417139J
Article type
Communication
Submitted
11 Nov 2004
Accepted
02 Dec 2004
First published
17 Dec 2004

Org. Biomol. Chem., 2005,3, 399-400

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Carbolithiation of gem-aryl disubstituted methylenecyclopropanes

J. Huang and M. Shi, Org. Biomol. Chem., 2005, 3, 399 DOI: 10.1039/B417139J

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