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Issue 43, 2019
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Biodegradable MnO2 nanosheet mediated hybridization chain reaction for imaging of human apurinic/apyrimidinic endonuclease 1 activity in living cells

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Abstract

A highly sensitive enzyme-free amplification assay for the detection of apurinic/apyrimidinic endonuclease 1 activity was developed. By incorporating biodegradable MnO2 nanosheets, in situ light up intracellular APE 1 activity was achieved.

Graphical abstract: Biodegradable MnO2 nanosheet mediated hybridization chain reaction for imaging of human apurinic/apyrimidinic endonuclease 1 activity in living cells

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Article information


Submitted
28 Jul 2019
Accepted
07 Oct 2019
First published
08 Oct 2019

Nanoscale, 2019,11, 20456-20460
Article type
Communication

Biodegradable MnO2 nanosheet mediated hybridization chain reaction for imaging of human apurinic/apyrimidinic endonuclease 1 activity in living cells

G. Li, J. Li and Q. Li, Nanoscale, 2019, 11, 20456
DOI: 10.1039/C9NR06436B

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