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Issue 32, 2017
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Atomic scale surface engineering of micro- to nano-sized pharmaceutical particles for drug delivery applications

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Abstract

Atomic layer deposition on pharmaceutical particles for drug delivery applications is demonstrated using assisted fluidized bed dry powder processing. Complete and conformal layering is achieved on particle sizes from the lower micron to upper nanometer range under near ambient conditions. As few as 2–14 atomic alumina layers alter particle properties: dissolution, dispersibility and heat transfer.

Graphical abstract: Atomic scale surface engineering of micro- to nano-sized pharmaceutical particles for drug delivery applications

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Article information


Submitted
08 May 2017
Accepted
25 Jun 2017
First published
27 Jun 2017

Nanoscale, 2017,9, 11410-11417
Article type
Communication

Atomic scale surface engineering of micro- to nano-sized pharmaceutical particles for drug delivery applications

D. Zhang, M. J. Quayle, G. Petersson, J. R. van Ommen and S. Folestad, Nanoscale, 2017, 9, 11410
DOI: 10.1039/C7NR03261G

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