Issue 42, 2016
From the journal:

Nanoscale

Studying the dynamic mechanism of transporting a single drug carrier-polyamidoamine dendrimer through cell membranes by force tracing†

Boyu Yang,a   Haijiao Xu,b   Shaowen Wang,d   Mingjun Cai,b   Yan Shi,b   Guocheng Yang,*a   Hongda Wang*bc  and  Yuping Shan*a  

* Corresponding authors

a School of Chemistry and Life Science, Advanced Institute of Materials Science, Changchun University of Technology, Changchun 130012, China
E-mail: shanyp@ciac.ac.cn

b State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Science, Renmin St 5625, Changchun, Jilin130022, China

c University of Chinese Academy of Sciences, Beijing, China
E-mail: hdwang@ciac.ac.cn

d Key Laboratory of Tropical Marine Bio-resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, China

Abstract

Although drug delivery based on nanomaterials has shown great potential in practical applications, the trans-membrane mechanism of the drug carrier is still unclear due to technical limitations. Here, we report the dynamic transporting process of a single dendritic polyamidoamine particle via cell membranes in real time by the force tracing technique.

Graphical abstract: Studying the dynamic mechanism of transporting a single drug carrier-polyamidoamine dendrimer through cell membranes by force tracing

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Article information

DOI
https://doi.org/10.1039/C6NR05838H
Article type
Communication
Submitted
24 Jul 2016
Accepted
29 Sep 2016
First published
30 Sep 2016

Nanoscale, 2016,8, 18027-18031

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Studying the dynamic mechanism of transporting a single drug carrier-polyamidoamine dendrimer through cell membranes by force tracing

B. Yang, H. Xu, S. Wang, M. Cai, Y. Shi, G. Yang, H. Wang and Y. Shan, Nanoscale, 2016, 8, 18027 DOI: 10.1039/C6NR05838H

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