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Issue 22, 2016
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Investigation of apoptotic events at molecular level induced by SERS guided targeted theranostic nanoprobe

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Abstract

Herein, we have examined distinctive structural and functional variations of cellular components during apoptotic cell death induced by a targeted theranostic nanoprobe, MMP-SQ@GNR@LAH-DOX, which acted as a SERS “on/off” probe in the presence of a MMP protease and executed synergistic photothermal chemotherapy, as reflected by the SERS fingerprinting, corresponding to the phosphodiester backbone of DNA.

Graphical abstract: Investigation of apoptotic events at molecular level induced by SERS guided targeted theranostic nanoprobe

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Publication details

The article was received on 26 Apr 2016, accepted on 04 May 2016 and first published on 05 May 2016


Article type: Communication
DOI: 10.1039/C6NR03385G
Citation: Nanoscale, 2016,8, 11392-11397

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    Investigation of apoptotic events at molecular level induced by SERS guided targeted theranostic nanoprobe

    N. Narayanan, L. V. Nair, V. Karunakaran, M. M. Joseph, J. B. Nair, R. A. N, R. S. Jayasree and K. K. Maiti, Nanoscale, 2016, 8, 11392
    DOI: 10.1039/C6NR03385G

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